Molecular Formula | C2H7Br2N |
Molar Mass | 204.89 |
Density | 1.9061 (rough estimate) |
Melting Point | 172 °C |
Boling Point | 181.3℃[at 101 325 Pa] |
Flash Point | 61°C |
Water Solubility | > 500 g/L (20 ºC) |
Solubility | >500g/l |
Vapor Presure | 0.001Pa at 25℃ |
Appearance | Crystalline Powder or Crystals |
Color | White to light beige |
BRN | 3607605 |
PH | 2.9 (10g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Sensitive | Hygroscopic |
Refractive Index | 1.5393 (estimate) |
Physical and Chemical Properties | Light yellow to white crystalline powder |
Use | For organic synthesis intermediates, pharmaceutical intermediates |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R68 - Possible risk of irreversible effects R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R43 - May cause sensitization by skin contact R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | KQ8225000 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Yes |
HS Code | 29211980 |
Hazard Note | Irritant |
Hazard Class | IRRITANT, CORROSIVE |
Toxicity | LD50 orally in Rabbit: > 200 - 2000 mg/kg |
Raw Materials | Hydrobromic acid Ethanolamine |
LogP | 0.795 at 25℃ |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
use | 2-bromoethylamine hydrobromide belongs to amine organic matter, which is an intermediate of important chemical products. 2-bromoethylamine hydrobromide belongs to amine organic matter, which is an intermediate of important chemical products. Used as organic synthesis intermediates, pharmaceutical intermediates, etc. Used as flux. Pharmaceutical intermediates, used in the production of emergency drugs Kenao Mi (AET) commonly used preservatives in biological products; It can also be used as a series of pharmaceutical intermediates in thiophene. It is also widely used in solder paste, lead-free solder and solder wire as an organic active agent. 2-bromoethylamine hydrobromide |
introduction | 2-bromoethylamine hydrobromide is an intermediate of important chemical products. at present, there are mainly two kinds of synthesis of 2-bromoethylamine hydrobromide. the liquid phase method is prepared by using ethanolamine and 48% hydrobromic acid as raw materials. the reaction time is as long as 48 hours. the gas phase rule is that ethanolamine is passed through human hydrogen bromide gas, although the gas phase method shortens the reaction time, it requires high equipment, is difficult to operate, and is easy to cause local overheating, and the reaction temperature is not easy to control. In this paper, the advantages of gas phase method and liquid phase method are absorbed. First, the salt formation reaction uses 48% hydrobromic acid, while the brinization reaction uses hydrogen bromide gas as raw material. |
Production method | is obtained by bromination of ethanolamine. Bromohydroacid is put into the reaction pot, cooled, stirred and added dropwise ethanolamine, the dropwise addition is completed within half an hour, and then the 85% amount of bromohydroacid is steamed out (the amount of bromohydroacid is 8.89 times the weight of ethanolamine), and the steam is finished in about 20 hours. After the concentrated solution is cooled to 70-80°C, it is placed in pre-frozen acetone, and then cooled to below 5°C to filter out the crystalline 2-bromoethylamine hydrobromide. 70% yield. |